About   Help   FAQ
Symbol
Name
ID
Tlr5
toll-like receptor 5
MGI:1858171
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Leukopenia
Pericarditis
Nephritis
Abnormality of the immune system
Malar rash
Antinuclear antibody positivity
Antiphospholipid antibody positivity
Systemic lupus erythematosus
Disease(s) Associated with TLR5
systemic lupus erythematosus

Mouse Phenotypes
immune system phenotype
abnormal leukocyte migration
increased susceptibility to colitis induced morbidity/mortality
increased susceptibility to induced colitis
large intestinal inflammation
increased susceptibility to induced pancreatitis
decreased neutrophil cell number
enlarged spleen
abnormal macrophage physiology
abnormal dendritic cell physiology
abnormal cytokine secretion
increased interleukin-1 beta secretion
decreased interleukin-12b secretion
decreased interleukin-6 secretion
increased susceptibility to autoimmune diabetes
lung inflammation
decreased susceptibility to bacterial infection
increased susceptibility to bacterial infection
abnormal response to transplant
Availability Mouse Genotype
Tlr5tm1Aki/Tlr5tm1Aki *
Tlr5tm1Flv/Tlr5tm1Flv
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr
Tg(Itgax-cre,-EGFP)4097Ach/?  (conditional)
*
Tg(Vil1-cre)997Gum/?
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory