Symbol Name ID |
Atoh7
atonal bHLH transcription factor 7 MGI:1355553 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Hemorrhage of the eye |
Hyphema |
Posterior synechiae of the anterior chamber |
Shallow anterior chamber |
Microcornea |
Corneal opacity |
Cataract |
Developmental cataract |
Leukocoria |
Persistent pupillary membrane |
Iris coloboma |
Buphthalmos |
Macular hypoplasia |
Retinal nonattachment |
Tractional retinal detachment |
Retinal fold |
Remnants of the hyaloid vascular system |
Glial remnants anterior to the optic disc |
Hyaloid vascular remnant and retrolental mass |
Uveitis |
Microphthalmia |
Phthisis bulbi |
Strabismus |
Esotropia |
Pendular nystagmus |
Reduced visual acuity |
Amblyopia |
Blindness |
Ultra-low vision with no light perception |
Glaucoma |
Angle closure glaucoma |
Epiphora |
Disease(s) Associated with ATOH7 | ||||||||||||||||||||||||||||||||
persistent hyperplastic primary vitreous |
Mouse Phenotypes | vision/eye phenotype |
abnormal retina vasculature morphology |
increased retina apoptosis |
abnormal Muller cell morphology |
decreased retina ganglion cell number |
absent retina ganglion cell |
decreased retina rod cell number |
increased amacrine cell number |
increased retina photoreceptor cell number |
increased retina cone cell number |
abnormal amacrine cell morphology |
abnormal retina bipolar cell morphology |
abnormal retina cone bipolar cell morphology |
abnormal retina rod bipolar cell morphology |
abnormal retina ganglion cell morphology |
abnormal retina cone cell morphology |
abnormal optic nerve morphology |
decreased optic chiasm size |
absent optic nerve |
optic nerve hypoplasia |
abnormal eye development |
abnormal optic vesicle formation |
abnormal retina morphology |
abnormal retina ganglion layer morphology |
absent retina ganglion layer |
thin retina inner nuclear layer |
thin retina inner plexiform layer |
abnormal retina nerve fiber layer morphology |
thin retina outer nuclear layer |
thin retina outer plexiform layer |
decreased total retina thickness |
abnormal eye electrophysiology |
abnormal rod electrophysiology |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
Atoh7tm1.1(Ascl1)Nlbr/Atoh7tm1.1(Ascl1)Nlbr | ||||||||||||||||||||||||||||||||||
Atoh7tm1Gan/Atoh7tm1Gan | ||||||||||||||||||||||||||||||||||
Atoh7tm1Gla/Atoh7tm1Gla | ||||||||||||||||||||||||||||||||||
Atoh7tm2Gan/Atoh7tm2Gan | ||||||||||||||||||||||||||||||||||
Atoh7tm3(cre)Gan/Atoh7tm3(cre)Gan | * | |||||||||||||||||||||||||||||||||
Atoh7tm1(Neurod1)Whk/Atoh7tm2(Neurod4)Whk | * | |||||||||||||||||||||||||||||||||
Atoh7tm1Gan/Atoh7tm1(Neurod1)Whk | ||||||||||||||||||||||||||||||||||
Atoh7tm1Gan/Atoh7tm2(Neurod4)Whk | ||||||||||||||||||||||||||||||||||
Atoh7tm1Gan/Atoh7tm2Gan |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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