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interleukin 27 receptor, alpha
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased T cell proliferation
increased lymphocyte cell number
abnormal T-helper 1 physiology
decreased circulating interferon-gamma level
increased circulating interferon-gamma level
increased circulating interleukin-1 beta level
increased circulating interleukin-12 level
increased circulating interleukin-4 level
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
decreased interferon-gamma secretion
increased interferon-gamma secretion
increased interleukin-4 secretion
decreased susceptibility to experimental autoimmune uveoretinitis
increased susceptibility to induced arthritis
decreased susceptibility to bacterial infection
increased susceptibility to bacterial infection
increased susceptibility to parasitic infection
Availability Mouse Genotype
Il27ratm1Mak/Il27ratm1Mak *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory