Symbol
Name
ID

Esr1
estrogen receptor 1 (alpha)
MGI:1352467

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Breast carcinoma	Telangiectasia	Vitiligo	Nevus	Sclerodactyly	Scleroderma
Disease(s) Associated with ESR1	Breast carcinoma	Telangiectasia	Vitiligo	Nevus	Sclerodactyly	Scleroderma
breast cancer
systemic scleroderma
vitiligo

Mouse Phenotypes

abnormal mammary gland morphology

abnormal mammary gland development

abnormal branching of the mammary ductal tree

abnormal mammary gland epithelium morphology

abnormal mammary gland duct morphology

mammary gland duct hyperplasia

abnormal mammary gland lobule morphology

abnormal mammary gland alveolus morphology

mammary gland alveolar hyperplasia

increased mammary gland ductal carcinoma incidence

abnormal lactation

Availability

Mouse Genotype

Esr1^tm1.1Gust/Esr1^tm1.1Gust

Esr1^tm1Geog/Esr1^tm1Geog

Esr1^tm1Ksk/Esr1^tm1Ksk

Esr1^tm2.1Gsc/Esr1^tm2.1Gsc

Esr1^tm3.1Ksk/Esr1^tm3.1Ksk

Esr1^tm4.2Ksk/Esr1^tm4.2Ksk

Esr1^tm1.1Lja/Esr1⁺

Tg(MMTV-rtTA)1Lach/0
Tg(tetO-Esr1)#Paf/0

Esr1^tm1Sakh/Esr1^tm1Sakh
Tg(MMTV-cre)4Mam/? (conditional)

Esr1^tm1Sakh/Esr1^tm1Sakh
Tg(Wap-cre)11738Mam/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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