Symbol
Name
ID

Esr1
estrogen receptor 1 (alpha)
MGI:1352467

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Abnormal abdomen morphology	Increased waist to hip ratio	Obesity
Disease(s) Associated with ESR1	Abnormal abdomen morphology	Increased waist to hip ratio	Obesity
coronary artery disease
systemic scleroderma
type 2 diabetes mellitus

Mouse Phenotypes

ovarian follicular cyst

ovary cyst

growth/size/body region phenotype

decreased birth weight

decreased body weight

increased body weight

obese

uterus cyst

decreased body length

increased body size

increased growth rate

Availability

Mouse Genotype

Esr1^tm1.1Gust/Esr1^tm1.1Gust

Esr1^tm1.1Ics/Esr1^tm1.1Ics

Esr1^tm1.1Mma/Esr1^tm1.1Mma

Esr1^tm1Geog/Esr1^tm1Geog

Esr1^tm1Ksk/Esr1^tm1Ksk

Esr1^tm3.1Ksk/Esr1^tm3.1Ksk

Esr1^tm4.2Ksk/Esr1^tm4.2Ksk

Esr1^tm1.1Lja/Esr1⁺

Esr1^tm1.2Awo/Esr1^tm1.2Awo
Kiss1^{tm1.1(cre)Uboe}/Kiss1⁺ (conditional)

Esr1^tm1.2Mma/Esr1^tm1.2Mma
Tg(Cga-cre)3Sac/0 (conditional)

Esr1^tm1.2Mma/Esr1^tm1.2Mma
Tg(Cyp17a1-icre)AJako/0 (conditional)

Esr1^tm1Syeh/Esr1^tm1Syeh
Tmem163^{Tg(ACTB-cre)2Mrt}/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23