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Symbol
Name
ID
Trp53bp1
transformation related protein 53 binding protein 1
MGI:1351320
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
small thymus
thymus hypoplasia
abnormal class switch recombination
abnormal T cell differentiation
increased double-negative T cell number
decreased mature B cell number
decreased B cell number
increased central memory CD4-positive, alpha-beta T cell number
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, naive alpha-beta T cell number
decreased T cell number
decreased IgD level
decreased IgG level
impaired humoral immune response
Availability Mouse Genotype
Trp53bp1Gt(OST94324)Lex/Trp53bp1Gt(OST94324)Lex
Trp53bp1m2Btlr/Trp53bp1m2Btlr
Trp53bp1m3Btlr/Trp53bp1m3Btlr
Trp53bp1m4Btlr/Trp53bp1m4Btlr
Trp53bp1m5Btlr/Trp53bp1m5Btlr
Trp53bp1tm1Jc/Trp53bp1tm1Jc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/08/2020
MGI 6.15
The Jackson Laboratory