Symbol
Name
ID

Ror2
receptor tyrosine kinase-like orphan receptor 2
MGI:1347521

Phenotype annotations related to limbs/digits/tail

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Radial bowing

Short middle phalanx of the 5th finger

Proximal/middle symphalangism of 5th finger

Clinodactyly of the 5th finger

Single interphalangeal crease of fifth finger

Aplasia/Hypoplasia of the distal phalanges of the hand

Short distal phalanx of finger

Duplication of the distal phalanx of hand

Short middle phalanx of finger

Camptodactyly of finger

Broad thumb

Radial deviation of finger

Broad hallux phalanx

Aplasia/Hypoplasia of the distal phalanges of the toes

Broad toe

Sandal gap

Toe syndactyly

Clinodactyly

Short digit

Brachydactyly

Type B brachydactyly

Syndactyly

Cutaneous finger syndactyly

Finger syndactyly

Bifid distal phalanx of toe

Dislocated radial head

Hypoplasia of the radius

Bilateral ulnar hypoplasia

Aplasia/Hypoplasia involving the metacarpal bones

Short palm

Small hand

Split hand

Synostosis of carpal bones

Bilateral single transverse palmar creases

Joint contracture of the hand

Elbow dislocation

Mesomelia

Mesomelic arm shortening

Disease(s) Associated with ROR2

autosomal recessive Robinow syndrome

brachydactyly type B1

Mouse Phenotypes

limbs/digits/tail phenotype

small tail bud

abnormal limb morphology

abnormal autopod morphology

abnormal digit morphology

abnormal phalanx morphology

brachyphalangia

brachydactyly

polydactyly

abnormal forelimb stylopod morphology

abnormal humerus morphology

short humerus

abnormal forelimb zeugopod morphology

abnormal radius morphology

short radius

abnormal ulna morphology

short ulna

abnormal hindlimb stylopod morphology

abnormal femur morphology

short femur

abnormal hindlimb zeugopod morphology

abnormal fibula morphology

short fibula

abnormal tibia morphology

short tibia

short metacarpal bones

abnormal limb development

abnormal digit development

short limbs

abnormal tail morphology

abnormal caudal vertebrae morphology

caudal vertebral fusion

small caudal vertebrae

abnormal tail development

short tail

kinked tail

Availability

Mouse Genotype

Ror2^em1(IMPC)Mbp/Ror2^em1(IMPC)Mbp

Ror2^tm1.2Meg/Ror2^tm1.2Meg

Ror2^tm1Anec/Ror2^tm1Anec

Ror2^tm1Gdy/Ror2^tm1Gdy

Ror2^tm1Ymi/Ror2^tm1Ymi

Ror2^{Tn(pb-ZG-s)1.1Mrc}/Ror2^{Tn(pb-ZG-s)1.1Mrc}

Ror2^Y324C/Ror2^Y324C

Ror2^tm1Anec/Ror2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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