Symbol
Name
ID

Abcg2
ATP binding cassette subfamily G member 2 (Junior blood group)
MGI:1347061

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Hypercalcemia

Elevated circulating creatinine concentration

Hyperproteinemia

Reduced leukocyte alkaline phosphatase

Pleural effusion

Fever

Abnormality of vitamin B12 metabolism

Amyloidosis

Disease(s) Associated with ABCG2

chronic myeloid leukemia

multiple myeloma

Mouse Phenotypes

homeostasis/metabolism phenotype

abnormal homeostasis

decreased blood urea nitrogen level

increased blood uric acid level

increased circulating bilirubin level

increased circulating glucose level

increased circulating insulin level

increased circulating insulin-like growth factor I level

increased circulating HDL cholesterol level

increased circulating cholesterol level

increased circulating potassium level

abnormal glucose homeostasis

impaired glucose tolerance

decreased liver glycogen level

increased urine sodium level

increased porphyrin level

porphyria

increased urine osmolality

increased urine uric acid level

phototoxicity

increased physiological sensitivity to xenobiotic

Availability

Mouse Genotype

Abcg2^em1Omw/Abcg2^em1Omw

Abcg2^{tm1.1(KOMP)Vlcg}/Abcg2^{tm1.1(KOMP)Vlcg}

Abcg2^tm1.1Ssf/Abcg2^tm1.1Ssf

Abcg2^tm1Ahs/Abcg2^tm1Ahs

Abcg2^tm1Bsor/Abcg2^tm1Bsor

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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