Symbol
Name
ID

Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
MGI:1346523

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes

Calf muscle hypertrophy

Calf muscle pseudohypertrophy

Scapular winging

Limb-girdle muscular dystrophy

Shoulder girdle muscle atrophy

Limb-girdle muscle weakness

Pelvic girdle muscle weakness

Difficulty walking

Muscle weakness

Gowers sign

Myotonia

Pelvic girdle muscle atrophy

Increased variability in muscle fiber diameter

Central core regions in muscle fibers

Proximal amyotrophy

Muscular dystrophy

Myopathy

Disease(s) Associated with SGCB

autosomal recessive limb-girdle muscular dystrophy type 2E

muscular dystrophy

Mouse Phenotypes

abnormal vascular smooth muscle morphology

myocardium necrosis

cardiomyopathy

skeletal muscle fiber necrosis

myositis

increased gastrocnemius weight

increased tibialis anterior weight

abnormal muscle morphology

abnormal sarcolemma morphology

centrally nucleated skeletal muscle fibers

skeletal muscle fiber degeneration

abnormal skeletal muscle morphology

calcified muscle

dystrophic muscle

muscular atrophy

Availability

Mouse Genotype

Sgcb^tm1Kcam/Sgcb^tm1Kcam

Sgcb^tm1Oza/Sgcb^tm1Oza

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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