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Symbol Name ID |
Nr0b2
nuclear receptor subfamily 0, group B, member 2 MGI:1346344 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased resting energy expenditure |
Type II diabetes mellitus |
Insulin resistance |
| Disease(s) Associated with NR0B2 | |||
| obesity | |||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
increased intestinal cholesterol absorption |
increased circulating testosterone level |
decreased circulating HDL cholesterol level |
decreased circulating LDL cholesterol level |
decreased circulating VLDL cholesterol level |
decreased circulating cholesterol level |
increased circulating alanine transaminase level |
increased circulating aspartate transaminase level |
abnormal lipid homeostasis |
abnormal bile salt homeostasis |
abnormal bile salt level |
increased bile salt level |
increased liver triglyceride level |
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| Availability | Mouse Genotype | ||||||||||||||
| Nr0b2tm1.1Auw/Nr0b2tm1.1Auw | |||||||||||||||
| Nr0b2tm1.1Mjev/Nr0b2tm1.1Mjev | * | ||||||||||||||
| Nr0b2tm1Ddm/Nr0b2tm1Ddm | |||||||||||||||
| Nr0b2tm1Rus/Nr0b2tm1Rus | |||||||||||||||
| Nr0b2tm1Mjev/Nr0b2tm1Mjev Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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