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toll-like receptor 2
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
altered response to myocardial infarction
increased insulin secretion
decreased macrophage nitric oxide production
abnormal circulating glucose level
abnormal circulating corticosterone level
decreased circulating corticosterone level
abnormal circulating insulin level
decreased circulating insulin level
decreased circulating leptin level
abnormal circulating pituitary hormone level
increased circulating adrenocorticotropin level
abnormal circulating lipid level
abnormal circulating cholesterol level
abnormal circulating LDL cholesterol level
decreased circulating VLDL cholesterol level
increased circulating free fatty acid level
decreased circulating interleukin-1 beta level
decreased circulating tumor necrosis factor level
decreased circulating alanine transaminase level
increased energy expenditure
abnormal glucose homeostasis
improved glucose tolerance
increased insulin sensitivity
abnormal chemokine level
abnormal interleukin level
abnormal tumor necrosis factor level
decreased cerebral infarction size
decreased susceptibility to kidney reperfusion injury
Availability Mouse Genotype
Tlr2tm1Aki/Tlr2tm1Aki *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory