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Symbol
Name
ID
Spry2
sprouty RTK signaling antagonist 2
MGI:1345138
Phenotype annotations related to skeleton
Darker colors indicate more annotations

Mouse Phenotypes
abnormal craniofacial bone morphology
wide intermaxillary suture
increased cranium height
abnormal neurocranium morphology
enlarged frontal bone
enlarged interparietal bone
small supraoccipital bone
abnormal temporal bone morphology
small neurocranium
abnormal diastema morphology
abnormal tooth morphology
abnormal molar cusp morphology
abnormal tooth development
supernumerary teeth
malocclusion
abnormal mandible morphology
abnormal mandibular condyloid process morphology
abnormal mandibular coronoid process morphology
short mandible
abnormal maxillary shelf morphology
short nasal bone
increased long bone epiphyseal plate size
decreased length of long bones
abnormal vertebral arch morphology
abnormal vertebral spinous process morphology
abnormal vertebral transverse process morphology
small vertebral body
spinal stenosis
decreased bone mineral density
decreased trabecular bone mass
abnormal chondrocyte morphology
Availability Mouse Genotype
Spry2tm1.1Mrt/Spry2tm1.1Mrt
Pax3tm1(cre)Joe/Pax3+
Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory