About Help FAQ

Symbol
Name
ID

Ldb3
LIM domain binding 3
MGI:1344412

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes

Calf muscle pseudohypertrophy

Peroneal muscle atrophy

Distal lower limb muscle weakness

Proximal muscle weakness in upper limbs

EMG: myopathic abnormalities

EMG: neuropathic changes

Difficulty running

Difficulty walking

Muscle stiffness

Progressive distal muscle weakness

Progressive muscle weakness

Progressive proximal muscle weakness

Autophagic vacuoles

Muscle fiber splitting

Distal amyotrophy

Myofibrillar myopathy

Rhabdomyolysis

Disease(s) Associated with LDB3

distal myopathy

myofibrillar myopathy 4

Mouse Phenotypes		abnormal myocardium layer morphology	abnormal myocardial fiber morphology	dilated cardiomyopathy	decreased cardiac muscle contractility	abnormal Z line morphology	skeletal muscle fiber atrophy	increased variability of skeletal muscle fiber size	abnormal skeletal muscle morphology	muscle weakness	myopathy
Availability	Mouse Genotype	abnormal myocardium layer morphology	abnormal myocardial fiber morphology	dilated cardiomyopathy	decreased cardiac muscle contractility	abnormal Z line morphology	skeletal muscle fiber atrophy	increased variability of skeletal muscle fiber size	abnormal skeletal muscle morphology	muscle weakness	myopathy
	Ldb3^tm1Chen/Ldb3^tm1Chen
	Ldb3^tm2Chen/Ldb3^tm2Chen
	Ldb3^tm3Chen/Ldb3^tm3Chen
	Ldb3^tm6.2Chen/Ldb3^tm6.2Chen
	Ldb3^tm4Chen/Ldb3^tm4Chen Myl2^tm1(cre)Krc/Myl2⁺ (conditional)
	Ldb3^tm4Chen/Ldb3^tm4Chen A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23