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Symbol
Name
ID

Mthfd1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
MGI:1342005

Phenotype annotations related to limbs/digits/tail

Darker colors indicate more annotations

Human Phenotypes	Short middle phalanx of the 5th finger	Clinodactyly of the 5th finger	Sandal gap	Clinodactyly	Brachydactyly	Short palm	Shallow acetabular fossae	Single transverse palmar crease	Bilateral single transverse palmar creases	Broad palm
Disease(s) Associated with MTHFD1	Short middle phalanx of the 5th finger	Clinodactyly of the 5th finger	Sandal gap	Clinodactyly	Brachydactyly	Short palm	Shallow acetabular fossae	Single transverse palmar crease	Bilateral single transverse palmar creases	Broad palm
Down syndrome
tetralogy of Fallot

Mouse Phenotypes		abnormal tail bud morphology	small tail bud
Availability	Mouse Genotype
	Mthfd1^tm1.1Rzn/Mthfd1^tm1.1Rzn

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23