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Symbol
Name
ID
Stk11
serine/threonine kinase 11
MGI:1341870
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Labial melanotic macule
Abnormal pigmentation of the oral mucosa
Oral melanotic macule
Abnormality of the nose
Nasal polyposis
Neoplasm of the nose
Disease(s) Associated with STK11
Peutz-Jeghers syndrome

Mouse Phenotypes
abnormal craniofacial morphology
abnormal basicranium morphology
small basisphenoid bone
small cranium
abnormal neurocranium morphology
large anterior fontanelle
small frontal bone
small parietal bone
abnormal sphenoid bone morphology
small presphenoid bone
small temporal bone squamous part
abnormal alveolar process morphology
short mandible
small premaxilla
small maxilla
micrognathia
abnormal nasal bone morphology
abnormal palatine bone morphology
small vomer bone
absent first pharyngeal arch
first pharyngeal arch hypoplasia
cleft secondary palate
short snout
Availability Mouse Genotype
Stk11tm1Tpm/Stk11tm1Tpm
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(PLAT-cre)116Sdu/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory