|
Symbol Name ID |
Rp1
retinitis pigmentosa 1 (human) MGI:1341105 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Attenuation of retinal blood vessels |
Optic disc pallor |
Bone spicule pigmentation of the retina |
Rod-cone dystrophy |
Undetectable light- and dark-adapted electroretinogram |
Myopia |
Nyctalopia |
Reduced visual acuity |
Constriction of peripheral visual field |
Scotoma |
| Disease(s) Associated with RP1 | ||||||||||
| retinitis pigmentosa 1 |
| Mouse Phenotypes | vision/eye phenotype |
abnormal retina vasculature morphology |
decreased retina photoreceptor cell number |
abnormal retina photoreceptor morphology |
disorganized photoreceptor inner segment |
short photoreceptor inner segment |
abnormal photoreceptor outer segment morphology |
short photoreceptor outer segment |
disorganized photoreceptor outer segment |
retina cone cell degeneration |
retina rod cell degeneration |
retina photoreceptor degeneration |
abnormal ocular fundus morphology |
abnormal retina neuronal layer morphology |
thin retina outer nuclear layer |
increased susceptibility to age-related retinal degeneration |
retina degeneration |
abnormal eye physiology |
decreased a-wave amplitude |
decreased b-wave amplitude |
abnormal eye electrophysiology |
abnormal cone electrophysiology |
abnormal rod electrophysiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Rp1m1Jdun/Rp1m1Jdun | ||||||||||||||||||||||||
| Rp1tm1Eap/Rp1tm1Eap | ||||||||||||||||||||||||
| Rp1tm1Jnz/Rp1tm1Jnz | ||||||||||||||||||||||||
| Rp1tm2.1Eap/Rp1tm2.1Eap | ||||||||||||||||||||||||
| Rp1tm2.1Eap/Rp1tm2.1Eap Tg(Rp1)T1Eap/0 |
* | |||||||||||||||||||||||
| Rp1tm2.1Eap/Rp1tm2.1Eap Tg(Rp1)L2Eap/0 |
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| Rp1tvrm64/Rp1tvrm64 | * | |||||||||||||||||||||||
| Rp1tm1Eap/Rp1+ | ||||||||||||||||||||||||
| Rp1tm1Jnz/Rp1+ | ||||||||||||||||||||||||
| Rp1tm1Jnz/Rp1tm1Eap | ||||||||||||||||||||||||
| Tg(Rp1)L2Eap/0 | * | |||||||||||||||||||||||
| Tg(Rp1)T1Eap/0 | * | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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