Symbol Name ID |
Mmp13
matrix metallopeptidase 13 MGI:1340026 |
Darker colors indicate more annotations |
Human Phenotypes | Radial bowing |
Ulnar bowing |
Femoral bowing |
Genu varum |
Tibial bowing |
Coxa vara |
Metaphyseal cupping |
Flared metaphysis |
Limited elbow extension |
Rhizomelia |
Delayed skeletal maturation |
Flattened epiphysis |
Small epiphyses |
Flared iliac wing |
Flared, irregular rib ends |
Irregular sclerotic endplates |
Pear-shaped vertebrae |
Platyspondyly |
Osteoarthritis |
Spondyloepimetaphyseal dysplasia |
Disease(s) Associated with MMP13 | ||||||||||||||||||||
spondyloepimetaphyseal dysplasia, Missouri type |
Mouse Phenotypes | abnormal bone healing |
short femur |
short tibia |
abnormal long bone hypertrophic chondrocyte zone |
increased width of hypertrophic chondrocyte zone |
increased long bone epiphyseal plate size |
abnormal trabecular bone morphology |
increased trabecular bone mass |
abnormal cartilage development |
delayed bone ossification |
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Availability | Mouse Genotype | ||||||||||
Mmp13em1(IMPC)Ccpcz/Mmp13em1(IMPC)Ccpcz | |||||||||||
Mmp13tm1.1Werb/Mmp13tm1.1Werb | |||||||||||
Mmp13tm1Jdar/Mmp13tm1Jdar | |||||||||||
Mmp13tm1Smk/Mmp13tm1Smk | |||||||||||
Mmp13tm1Werb/Mmp13tm1Werb Tg(Col1a1-cre)1Kry/0 (conditional) |
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Mmp13tm1Werb/Mmp13tm1Werb Tg(Col2a1-cre)1Rsjo/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/12/2024 MGI 6.23 |
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