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Symbol
Name
ID

Csf1
colony stimulating factor 1 (macrophage)
MGI:1339753

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Mouse Phenotypes

increased osteocyte apoptosis

impaired osteoblast differentiation

abnormal osteoclast differentiation

abnormal osteoblast physiology

abnormal parietal bone morphology

absent incisors

abnormal dental follicle morphology

abnormal dentin mineralization

abnormal predentin morphology

failure of tooth eruption

abnormal tooth root development

absent teeth

domed cranium

decreased osteoclast cell number

abnormal osteoclast morphology

abnormal osteoclast cell number

abnormal femur morphology

abnormal tibia morphology

abnormal skeleton morphology

abnormal long bone hypertrophic chondrocyte zone

increased width of hypertrophic chondrocyte zone

increased long bone epiphyseal plate size

decreased length of long bones

abnormal bone structure

abnormal bone marrow cavity morphology

abnormal bone marrow morphology

increased trabecular bone volume

abnormal compact bone morphology

decreased compact bone thickness

abnormal osteoblast morphology

abnormal osteocyte morphology

abnormal osteocyte dendritic process morphology

abnormal osteocyte lacuna morphology

abnormal trabecular bone morphology

increased bone trabecula number

increased trabecular bone mass

decreased trabecular bone thickness

osteoporosis

increased bone mass

osteopetrosis

osteosclerosis

decreased bone mineralization

abnormal bone remodeling

decreased bone resorption

fragile skeleton

Availability

Mouse Genotype

Csf1^op/Csf1^op

Csf1^tm1.2Sabw/Csf1^tm1.2Sabw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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