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Symbol Name ID |
Lig4
ligase IV, DNA, ATP-dependent MGI:1335098 |
| Darker colors indicate more annotations |
| Human Phenotypes | Acute lymphoblastic leukemia |
Multiple myeloma |
Myelodysplasia |
Breast carcinoma |
Hereditary nonpolyposis colorectal carcinoma |
Colon cancer |
Neoplasm of the stomach |
Neoplasm of the liver |
Pancreatic adenocarcinoma |
Prostate cancer |
Ovarian carcinoma |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Melanoma |
| Disease(s) Associated with LIG4 | |||||||||||||||
| colorectal cancer | |||||||||||||||
| DNA ligase IV deficiency | |||||||||||||||
| multiple myeloma | |||||||||||||||
| pancreatic cancer | |||||||||||||||
| prostate cancer |
| Mouse Phenotypes | increased colon adenocarcinoma incidence |
increased T cell derived lymphoma incidence |
increased medulloblastoma incidence |
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| Availability | Mouse Genotype | |||
| Lig4tm2.1Fwa/Lig4tm2.1Fwa | ||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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