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Symbol
Name
ID
Dyrk1a
dual-specificity tyrosine phosphorylation regulated kinase 1a
MGI:1330299
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Feeding difficulties in infancy
Happy demeanor
Inappropriate laughter
Autism
Hyperactivity
Motor stereotypy
Stereotypical hand wringing
Disease(s) Associated with DYRK1A
autosomal dominant intellectual developmental disorder 7

Mouse Phenotypes
impaired spatial learning
abnormal long-term spatial reference memory
cognitive inflexibility
decreased aggression towards mice
decreased vertical activity
decreased social investigation
abnormal vocalization
decreased vocalization
environmentally induced seizures
Availability Mouse Genotype
Dyrk1aem1Kzy/Dyrk1a+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory