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Symbol
Name
ID
Orc1
origin recognition complex, subunit 1
MGI:1328337
Phenotype annotations related to mortality/aging
Darker colors indicate more annotations
Human Phenotypes
Death in infancy
Disease(s) Associated with ORC1
Meier-Gorlin syndrome 1

Mouse Phenotypes
embryonic lethality prior to organogenesis
embryonic lethality at implantation, complete penetrance
embryonic lethality, complete penetrance
prenatal lethality prior to heart atrial septation
preweaning lethality, complete penetrance
Availability Mouse Genotype
Orc1tm1.2Gle/Orc1tm1.2Gle
Orc1tm1a(KOMP)Wtsi/Orc1tm1a(KOMP)Wtsi
Orc1tm1b(KOMP)Wtsi/Orc1tm1b(KOMP)Wtsi
Orc1tm1.1Gle/Orc1tm1.2Gle
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory