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Symbol
Name
ID

Tnfrsf11a
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
MGI:1314891

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Hypercalcemia	Hypocalcemic seizures	Elevated circulating alkaline phosphatase concentration	Hydroxyprolinuria
Disease(s) Associated with TNFRSF11A	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Hypercalcemia	Hypocalcemic seizures	Elevated circulating alkaline phosphatase concentration	Hydroxyprolinuria
autosomal recessive osteopetrosis 7
familial expansile osteolysis
Paget's disease of bone 2

Mouse Phenotypes		abnormal body temperature homeostasis	abnormal circadian temperature homeostasis	impaired febrile response	decreased prostaglandin level	decreased tumor necrosis factor (ligand) superfamily member 11 level	abnormal response/metabolism to endogenous compounds
Availability	Mouse Genotype	abnormal body temperature homeostasis	abnormal circadian temperature homeostasis	impaired febrile response	decreased prostaglandin level		abnormal response/metabolism to endogenous compounds
	Tnfrsf11a^tm1.1Sral/Tnfrsf11a⁺
	Tnfrsf11a^tm1.1Pngr/Tnfrsf11a^tm1.2Pngr Tg(Nes-cre)1Kln/0 (conditional)
	Tnfrsf11a^tm1.1Pngr/Tnfrsf11a^tm1.2Pngr Tg(Gfap-cre)2Brn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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