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Symbol
Name
ID
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
MGI:1314884
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Bruising susceptibility
Leukocytosis
Elevated erythrocyte sedimentation rate
Splenomegaly
Disease(s) Associated with TNFRSF1A
autosomal dominant familial periodic fever

Mouse Phenotypes
increased basophil cell number
increased eosinophil cell number
decreased red blood cell distribution width
decreased neutrophil cell number
increased neutrophil cell number
increased lymphocyte cell number
increased large unstained cell number
decreased monocyte cell number
increased leukocyte cell number
decreased microglial cell number
decreased spleen weight
abnormal spleen germinal center morphology
decreased IgG1 level
decreased IgG level
abnormal macrophage physiology
Availability Mouse Genotype
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
Tnfrsf1atm1Rsie/Tnfrsf1atm1Rsie
Tnfrsf1atm2.1Rsie/Tnfrsf1atm2.1Rsie
Tnfrsf1atm2b(EUCOMM)Wtsi/Tnfrsf1atm2b(EUCOMM)Wtsi
Tnfrsf1atm2.1Rsie/Tnfrsf1a+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory