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Symbol
Name
ID
Dlg4
discs large MAGUK scaffold protein 4
MGI:1277959
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
nervous system phenotype
abnormal forebrain morphology
abnormal striatum morphology
abnormal hippocampus pyramidal cell morphology
abnormal innervation
abnormal dendritic spine morphology
abnormal synaptic plasticity
abnormal synaptic transmission
abnormal CNS synaptic transmission
abnormal glutamate-mediated receptor currents
abnormal AMPA-mediated synaptic currents
reduced AMPA-mediated synaptic currents
abnormal NMDA-mediated synaptic currents
enhanced long term potentiation
decreased neurotransmitter release
enhanced paired-pulse facilitation
Availability Mouse Genotype
Dlg4tm1.1Tdoi/Dlg4tm1.1Tdoi
Dlg4tm1Grnt/Dlg4tm1Grnt
Dlg4tm1Rlh/Dlg4tm1Rlh
Dlg4tm2.1Grnt/Dlg4tm2.1Grnt *
Dlg4tm3.1Grnt/Dlg4tm3.1Grnt *
Dlg4tm4.1Grnt/Dlg4tm4.1Grnt *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory