Symbol
Name
ID

Tyrobp
TYRO protein tyrosine kinase binding protein
MGI:1277211

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Limitation of joint mobility	Bone pain	Pathologic fracture	Abnormal epiphysis morphology	Reduced bone mineral density	Bone cyst	Skeletal dysplasia	Cerebral calcification	Basal ganglia calcification
Disease(s) Associated with TYROBP
Nasu-Hakola disease

Mouse Phenotypes

abnormal osteoclast differentiation

abnormal osteoclast morphology

abnormal osteoclast physiology

decreased susceptibility to induced arthritis

increased bone mineral density of caudal vertebrae

increased bone mineral content

increased bone mineral density of femur

increased bone mineral density

increased trabecular bone volume

increased bone trabecula number

increased trabecular bone mass

increased bone mass

osteopetrosis

abnormal bone ossification

abnormal bone remodeling

decreased bone resorption

Availability

Mouse Genotype

Tyrobp^tm1.1Viv/Tyrobp^tm1.1Viv

Tyrobp^tm1Lll/Tyrobp^tm1Lll

Tyrobp^tm1Ttk/Tyrobp^tm1Ttk

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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