Symbol
Name
ID

Atg5
autophagy related 5
MGI:1277186

Phenotype annotations related to cellular

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

cellular phenotype

abnormal sperm flagellum morphology

abnormal sperm end piece morphology

abnormal sperm midpiece morphology

abnormal sperm mitochondrial sheath morphology

absent sperm fibrous sheath

short sperm flagellum

oligozoospermia

teratozoospermia

abnormal sperm head morphology

abnormal acrosome assembly

globozoospermia

abnormal sperm nucleus morphology

double-headed sperm

multinucleated giant male germ cells

abnormal intestinal goblet cell morphology

increased mitochondrial size

abnormal lysosome morphology

abnormal cell physiology

abnormal autophagy

impaired autophagy

asthenozoospermia

immotile sperm

decreased T cell proliferation

oxidative stress

Availability

Mouse Genotype

Atg5^tm1Myok/Atg5^tm1Myok

Atg5^tm1Nmz/Atg5^tm1Nmz

Atg5^tm1Myok/Atg5^tm1Myok
Tg(Nes-cre)1Kln/? (conditional)

Atg5^tm1Myok/Atg5^tm1Myok
Tg(Vil1-cre)997Gum/0 (conditional)

Atg5^tm1Myok/Atg5^tm1Myok
Tg(Kap-cre)1Isa/0 (conditional)

Atg5^tm1Myok/Atg5^tm1Myok
Tg(BEST1-cre)1Taf/0 (conditional)

Atg5^tm1Myok/Atg5^tm1Myok
Tg(Vil1-cre)1000Gum/0 (conditional)

Atg5^tm1Myok/Atg5^tm1Myok
Tg(Pomc1-cre)1Gsb/0 (conditional)

Atg5^tm1Myok/Atg5^tm1Myok
Tg(Stra8-icre)1Reb/0 (conditional)

Atg5^tm1Nmz/Atg5^tm1Nmz
Tg(Cd4-cre)1Cwi/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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