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Symbol
Name
ID
Cdk6
cyclin-dependent kinase 6
MGI:1277162
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
decreased thymocyte apoptosis
increased T cell apoptosis
decreased T cell proliferation
abnormal thymus morphology
thymus cortex atrophy
enlarged thymus
small thymus
thymus atrophy
thymus hypoplasia
decreased thymocyte number
decreased DN1 thymic pro-T cell number
decreased DN2 thymocyte number
decreased DN4 thymocyte number
increased thymocyte number
increased DN1 thymic pro-T cell number
increased DN3 thymocyte number
abnormal thymocyte activation
abnormal hematopoietic system morphology/development
abnormal definitive hematopoiesis
abnormal lymphopoiesis
abnormal T cell differentiation
decreased double-negative T cell number
increased double-negative T cell number
decreased double-positive T cell number
decreased megakaryocyte cell number
abnormal erythrocyte morphology
decreased erythrocyte cell number
increased mean corpuscular hemoglobin concentration
increased mean corpuscular volume
increased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
increased single-positive T cell number
decreased leukocyte cell number
decreased hematopoietic stem cell number
increased hematopoietic stem cell number
abnormal spleen morphology
abnormal spleen red pulp morphology
small spleen
spleen hypoplasia
abnormal hematopoietic stem cell physiology
Availability Mouse Genotype
Cdk6tm1Bbd/Cdk6tm1Bbd
Cdk6tm1Phin/Cdk6tm1Phin
Cdk6tm2.1Phin/Cdk6tm2.1Phin
Cdk6tm3.1Phin/Cdk6tm3.1Phin
Cdk6tm4.1Phin/Cdk6tm4.1Phin

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory