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Symbol
Name
ID
Casp8
caspase 8
MGI:1261423
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Breast carcinoma
Jaundice
Eczematoid dermatitis
Disease(s) Associated with CASP8
autoimmune lymphoproliferative syndrome type 2B
breast cancer
pancreatic cancer

Mouse Phenotypes
abnormal skin vasculature morphology
skin edema
epidermal spongiosis
impaired skin barrier function
dermatitis
abnormal skin morphology
abnormal epidermal layer morphology
acanthosis
abnormal keratinocyte morphology
epidermal hyperplasia
thick epidermis
dry skin
scaly skin
Availability Mouse Genotype
Casp8tm1Hed/Casp8tm1Hed
Tg(KRT14-cre)1Efu/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory