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Symbol
Name
ID
Casp8
caspase 8
MGI:1261423
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Defective B cell activation
Decreased T cell activation
Disease(s) Associated with CASP8
autoimmune lymphoproliferative syndrome type 2B

Mouse Phenotypes
hemopericardium
pericardial edema
abnormal circulating enzyme level
skin edema
epidermal spongiosis
impaired skin barrier function
abnormal response/metabolism to endogenous compounds
decreased susceptibility to injury
increased susceptibility to injury
Availability Mouse Genotype
Casp8tm1Syon/Casp8tm1Syon
Casp8tm1Clie/Casp8tm1Clie
Tg(Alb1-cre)7Gsc/0  (conditional)
Casp8tm1Hed/Casp8tm1Hed
Tg(KRT14-cre)1Efu/0  (conditional)
Casp8tm1Wll/Casp8tm1.1Yuan
Tg(Alb1-cre)7Gsc/0  (conditional)
Casp8tm1Wll/Casp8tm1.1Yuan
Tg(Tie1-cre)9Ref/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory