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Symbol
Name
ID

Dsg2
desmoglein 2
MGI:1196466

Phenotype annotations related to mortality/aging

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Sudden cardiac death
Disease(s) Associated with DSG2	Sudden cardiac death
arrhythmogenic right ventricular dysplasia 10

Mouse Phenotypes		increased susceptibility to colitis induced morbidity/mortality	increased susceptibility to induced morbidity/mortality	embryonic lethality during organogenesis, incomplete penetrance	embryonic lethality at implantation, complete penetrance	embryonic lethality between implantation and somite formation, incomplete penetrance	preweaning lethality, incomplete penetrance
Availability	Mouse Genotype		increased susceptibility to induced morbidity/mortality		embryonic lethality at implantation, complete penetrance		preweaning lethality, incomplete penetrance
	Dsg2^em1Spin/Dsg2^em1Spin
	Dsg2^{tm1b(EUCOMM)Wtsi}/Dsg2^{tm1b(EUCOMM)Wtsi}
	Dsg2^{tm1d(EUCOMM)Wtsi}/Dsg2^{tm1d(EUCOMM)Wtsi}
	Dsg2^tm1Leu/Dsg2^tm1Leu
	Dsg2^tm1Leu/Dsg2⁺					!
	Dsg2^tm3.1Leu/Dsg2^tm3.1Leu Tg(Vil1-cre)20Syr/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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