Symbol Name ID |
Polg
polymerase (DNA directed), gamma MGI:1196389 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased activity of mitochondrial complex I |
Decreased activity of mitochondrial complex IV |
Disease(s) Associated with POLG | ||
mitochondrial DNA depletion syndrome 4b |
Mouse Phenotypes | azoospermia |
oligozoospermia |
increased mitochondrial size |
increased apoptosis |
abnormal mitochondrial ATP synthesis coupled electron transport |
abnormal mitochondrial physiology |
abnormal oxidative phosphorylation |
oxidative stress |
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Availability | Mouse Genotype | ||||||||
Polgtm1.1Lrsn/Polgtm1.1Lrsn | |||||||||
Polgtm1Jiha/Polgtm1Jiha | |||||||||
Polgtm1Prol/Polgtm1Prol | |||||||||
Polgtm1Jiha/Polg+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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