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Symbol
Name
ID

Polg
polymerase (DNA directed), gamma
MGI:1196389

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Abdominal pain	Depression	Emotional lability	Apathy	Reduced social reciprocity	Impulsivity	Agitation	Restless legs	Dysphonia	Hypernasal speech
Disease(s) Associated with POLG	Abdominal pain	Depression	Emotional lability	Apathy	Reduced social reciprocity	Impulsivity	Agitation	Restless legs	Dysphonia	Hypernasal speech
autosomal dominant progressive external ophthalmoplegia 1
autosomal recessive progressive external ophthalmoplegia 1
mitochondrial DNA depletion syndrome 4b
Parkinson's disease
sensory ataxic neuropathy, dysarthria, and ophthalmoparesis

Mouse Phenotypes		behavior/neurological phenotype	decreased food intake	increased fear-related response	increased startle reflex	abnormal voluntary movement	abnormal ultradian rhythm behavior
Availability	Mouse Genotype
	Tg(Camk2a-Polg*D181A)BTkato/0	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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