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Symbol
Name
ID
Ilk
integrin linked kinase
MGI:1195267
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal glomerular capillary morphology
detached podocyte
increased metanephric mesenchyme apoptosis
increased kidney apoptosis
increased podocyte apoptosis
increased urine protein level
albuminuria
tubulointerstitial nephritis
abnormal kidney morphology
decreased kidney collecting duct number
abnormal podocyte morphology
fused podocyte foot processes
podocyte foot process effacement
abnormal podocyte slit diaphragm morphology
decreased podocyte number
podocyte microvillus transformation
abnormal renal glomerulus basement membrane morphology
increased renal glomerulus basement membrane thickness
abnormal renal glomerulus morphology
expanded mesangial matrix
glomerulosclerosis
glomerular crescent
renal glomerular synechia
renal glomerulus hypertrophy
renal interstitial fibrosis
renal tubule atrophy
renal hypoplasia
decreased nephron number
dilated renal tubules
absent kidney
single kidney
absent ureter
abnormal ureteric bud morphology
impaired branching involved in ureteric bud morphogenesis
abnormal ureteric bud invasion
abnormal glomerular filtration barrier function
kidney failure
anuria
Availability Mouse Genotype
Ilktm8.1Ref/Ilktm8.1Ref
Ilktm9.1Ref/Ilktm9.1Ref
Ilktm1Star/Ilktm1Star
Tg(NPHS2-cre)295Lbh/0  (conditional)
Ilktm3Ref/Ilktm3Ref  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory