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Symbol Name ID |
Kl
klotho MGI:1101771 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cervical spondylosis |
Spondylolisthesis |
Spondylolysis |
Osteoporosis |
Gout |
Osteoarthritis |
| Disease(s) Associated with KL | ||||||
| coronary artery disease | ||||||
| spondylosis |
| Mouse Phenotypes | abnormal osteoblast physiology |
thick zygomatic arch |
abnormal middle ear ossicle morphology |
abnormal incus morphology |
abnormal malleus morphology |
abnormal malleus manubrium morphology |
short malleus manubrium |
short malleus |
small stapes obturator foramen |
decreased osteoclast cell number |
abnormal osteoclast morphology |
abnormal femur morphology |
decreased femur compact bone thickness |
short femur |
short tibia |
abnormal tracheal cartilage morphology |
abnormal long bone epiphyseal plate proliferative zone |
decreased width of hypertrophic chondrocyte zone |
decreased long bone epiphyseal plate size |
abnormal long bone epiphysis morphology |
small pubis |
abnormal rib morphology |
wide ribs |
kyphosis |
kyphoscoliosis |
abnormal vertebrae morphology |
abnormal bone structure |
decreased bone mineral content |
abnormal bone mineral density |
decreased bone mineral density of femur |
decreased bone mineral density |
decreased compact bone thickness |
abnormal osteoblast morphology |
decreased osteoblast cell number |
abnormal trabecular bone morphology |
absent bone trabeculae |
osteoporosis |
osteopetrosis |
abnormal bone ossification |
decreased bone ossification |
decreased bone resorption |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||
| Klecalc1/Klecalc1 | ||||||||||||||||||||||||||||||||||||||||||
| Klecalc2/Klecalc2 | ||||||||||||||||||||||||||||||||||||||||||
| Klem1Btlr/Klem1Btlr | ||||||||||||||||||||||||||||||||||||||||||
| Klkl/Klkl | ||||||||||||||||||||||||||||||||||||||||||
| Klm1Anu/Klm1Anu | ||||||||||||||||||||||||||||||||||||||||||
| Kltm1.2Tel/Kltm1.2Tel | ||||||||||||||||||||||||||||||||||||||||||
| Kltm1Lex/Kltm1Lex | ||||||||||||||||||||||||||||||||||||||||||
| Kltm1Yin/Kltm1Yin | ||||||||||||||||||||||||||||||||||||||||||
| Klkl/Kl+ | ||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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