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Symbol
Name
ID
Npc1
NPC intracellular cholesterol transporter 1
MGI:1097712
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
abnormal Golgi apparatus morphology
absent sperm flagellum
abnormal primary cilium morphology
increased macrophage derived foam cell number
foam cell reticulosis
oligozoospermia
teratozoospermia
abnormal sperm head morphology
absent sperm head
abnormal mitochondrion morphology
abnormal mitochondrial crista morphology
abnormal mitochondrial matrix morphology
abnormal mitochondrial shape
abnormal plasma membrane sphingolipid content
increased plasma membrane sphingolipid content
sphingomyelinosis
abnormal cellular cholesterol metabolism
abnormal lysosome physiology
abnormal mitochondrial physiology
impaired acrosome reaction
Availability Mouse Genotype
Npc1m1N/Npc1m1N
Npc1nmf164/Npc1nmf164
Npc1spm/Npc1spm
Npc1tm1.1Dso/Npc1tm1.1Dso
Npc1tm1Mbjg/Npc1tm1Mbjg
Npc1m1N/Npc1tm1.2Apl

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory