About   Help   FAQ
Symbol
Name
ID
Cd81
CD81 antigen
MGI:1096398
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating IgA level
Decreased circulating IgG level
Decreased circulating total IgM
Decreased antibody level in blood
Impaired T cell function
Autoimmune hemolytic anemia
Neutropenia
Neutropenia in presence of anti-neutropil antibodies
Lymphopenia
B lymphocytopenia
Autoimmune thrombocytopenia
Recurrent sinusitis
Recurrent bronchitis
Conjunctivitis
Lymphadenopathy
Follicular hyperplasia
Splenomegaly
Inflammation of the large intestine
Colitis
Otitis media
Chronic otitis media
Recurrent otitis media
Glomerulonephritis
Psoriasiform dermatitis
Pneumonia
Recurrent pneumonia
Autoimmunity
Immunodeficiency
Asthma
Recurrent infections
Recurrent bacterial infections
Recurrent respiratory infections
Meningitis
Disease(s) Associated with CD81
common variable immunodeficiency

Mouse Phenotypes
decreased B cell proliferation
increased B cell proliferation
abnormal T cell proliferation
abnormal B cell differentiation
decreased B-1 B cell number
decreased B-1a cell number
abnormal B cell morphology
abnormal microglial cell morphology
increased IgA level
decreased IgG1 level
increased IgG3 level
decreased IgG level
increased IgM level
abnormal T-helper 2 physiology
abnormal macrophage physiology
abnormal immune system cell morphology
decreased susceptibility to type I hypersensitivity reaction
decreased susceptibility to parasitic infection
Availability Mouse Genotype
Cd81tm1Geha/Cd81tm1Geha
Cd81tm1Lvy/Cd81tm1Lvy
Cd81tm1Tmiy/Cd81tm1Tmiy

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/05/2019
MGI 6.14
The Jackson Laboratory