Symbol Name ID |
Ptprq
protein tyrosine phosphatase receptor type Q MGI:1096349 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal vestibular function |
Sensorineural hearing impairment |
Hearing impairment |
Disease(s) Associated with PTPRQ | |||
autosomal dominant nonsyndromic deafness 73 | |||
autosomal recessive nonsyndromic deafness 84A |
Mouse Phenotypes | abnormal cochlear hair cell stereociliary bundle morphology |
abnormal inner hair cell stereociliary bundle morphology |
abnormal orientation of inner hair cell stereociliary bundles |
decreased inner hair cell stereocilia number |
fused inner hair cell stereocilia |
abnormal outer hair cell stereociliary bundle morphology |
short outer hair cell stereocilia |
cochlear hair cell degeneration |
organ of Corti degeneration |
abnormal vestibular hair cell stereociliary bundle morphology |
absent vestibular hair bundle shaft connectors |
abnormal hair cell mechanoelectric transduction |
increased susceptibility to age-related hearing loss |
deafness |
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Availability | Mouse Genotype | ||||||||||||||
Ptprqmpc205H/Ptprqmpc205H | |||||||||||||||
Ptprqtm1Bow/Ptprqtm1Bow | |||||||||||||||
Ptprqtm2Bow/Ptprqtm2Bow |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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