About   Help   FAQ
Symbol
Name
ID
Ptprq
protein tyrosine phosphatase receptor type Q
MGI:1096349
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations
Human Phenotypes
Abnormal vestibular function
Sensorineural hearing impairment
Hearing impairment
Disease(s) Associated with PTPRQ
autosomal dominant nonsyndromic deafness 73
autosomal recessive nonsyndromic deafness 84A

Mouse Phenotypes
abnormal cochlear hair cell stereociliary bundle morphology
abnormal inner hair cell stereociliary bundle morphology
abnormal orientation of inner hair cell stereociliary bundles
decreased inner hair cell stereocilia number
fused inner hair cell stereocilia
abnormal outer hair cell stereociliary bundle morphology
short outer hair cell stereocilia
cochlear hair cell degeneration
organ of Corti degeneration
abnormal vestibular hair cell stereociliary bundle morphology
absent vestibular hair bundle shaft connectors
abnormal hair cell mechanoelectric transduction
increased susceptibility to age-related hearing loss
deafness
Availability Mouse Genotype
Ptprqmpc205H/Ptprqmpc205H
Ptprqtm1Bow/Ptprqtm1Bow
Ptprqtm2Bow/Ptprqtm2Bow

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory