About   Help   FAQ
Symbol
Name
ID 		Pten
phosphatase and tensin homolog
MGI:109583
Phenotype annotations related to mortality/aging
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
mortality/aging
premature ovarian failure
decreased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to induced morbidity/mortality
decreased tumor-free survival time
lethality at weaning, complete penetrance
decreased survivor rate
premature death
lethality throughout fetal growth and development, incomplete penetrance
neonatal lethality, complete penetrance
neonatal lethality, incomplete penetrance
postnatal lethality, complete penetrance
postnatal lethality, incomplete penetrance
embryonic lethality
embryonic lethality during organogenesis, complete penetrance
embryonic lethality during organogenesis, incomplete penetrance
embryonic lethality between implantation and somite formation, complete penetrance
embryonic lethality, complete penetrance
prenatal lethality, incomplete penetrance
preweaning lethality, complete penetrance
Availability Mouse Genotype
Ptenm1un/Ptenm1un
Ptentm1.1Gle/Ptentm1.1Gle
Ptentm1.1Hwu/Ptentm1.1Hwu
Ptentm1.1Mro/Ptentm1.1Mro
Ptentm1.1Yxy/Ptentm1.1Yxy
Ptentm1.2Mwst/Ptentm1.2Mwst
Ptentm1Mak/Ptentm1Mak
Ptentm1Ppp/Ptentm1Ppp
Ptentm1Rps/Ptentm1Rps
Ptentm2.1Gle/Ptentm2.1Gle
Ptentm1Mak/Pten+
Ptentm1Ppp/Ptentm2Ppp
Ptentm1Rps/Pten+
Ptentm1Hwu/Ptentm1Hwu
Tg(KRT14-cre)#Smr/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0  (conditional)		 *
Ptentm1Hwu/Ptentm1Hwu
Tg(Cr2-cre)3Cgn/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Nes-cre)1Atp/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(GFAP-cre)25Mes/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Pdx1-cre)89.1Dam/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Cnptm1(cre)Kan/Cnp+  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Gdf9-icre)5092Coo/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Fabp1-cre)1Jig/0  (conditional)
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Tyr-cre)1Lru/0  (conditional)
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu  (conditional)
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Nkx2-1-cre)2Sand/0  (conditional)		 *!
Ptentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+  (conditional)
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(TPO-cre)1Shk/0  (conditional)
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(Dhh-cre)1Mejr/0  (conditional)
Ptentm2Mak/Ptentm2Mak
Tg(Gfap-cre)1Sbk/0  (conditional)
Ptentm2Mak/Ptentm2Mak
Tg(Col2a1-cre)1Xya/?  (conditional)
Ptentm2Mak/Ptentm2Mak
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0  (conditional)
Ptentm2Mak/Ptentm2Mak
Tg(Hoxb7-cre)5526Cmb/0  (conditional)
Ptentm2Mak/Ptentm2Mak
Tg(KLK3-cre)13Saa/0  (conditional)
Ptentm2Mak/Ptentm2Mak
Tg(Nes-cre/ERT2,-ALPP)1Sbk/0  (conditional)
Ptentm1Hwu/Pten+
Tg(KRT14-cre)#Smr/0  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory