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Symbol
Name
ID
Adam10
a disintegrin and metallopeptidase domain 10
MGI:109548
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal granulocyte differentiation
small thymus
thymus hypoplasia
abnormal B cell differentiation
decreased transitional stage T2 B cell number
increased transitional stage T1 B cell number
abnormal T cell differentiation
decreased double-positive T cell number
myeloid hyperplasia
increased neutrophil cell number
absent marginal zone B cells
increased follicular B cell number
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased T cell number
increased leukocyte cell number
abnormal spleen morphology
increased spleen red pulp amount
increased spleen weight
enlarged spleen
spleen hyperplasia
Availability Mouse Genotype
Adam10tm1.1Dhc/Adam10tm1.1Dhc
Cd19tm1(cre)Cgn/Cd19+  (conditional)
Adam10tm1.1Khr/Adam10tm1.1Khr
Tg(Mx1-cre)1Cgn/0  (conditional)
Adam10tm1Zhu/Adam10tm1Zhu
Tg(Lck-cre)#Zhu/0  (conditional)
Adam10tm1Zhu/Adam10tm1.1Zhu
Tg(Lck-cre)#Zhu/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory