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Symbol
Name
ID
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
MGI:1095407
Phenotype annotations related to respiratory system
Darker colors indicate more annotations
Human Phenotypes
Elevated pulmonary artery pressure
Pulmonary arterial hypertension
Increased pulmonary vascular resistance
Pulmonary arterial medial hypertrophy
Pulmonary aterial intimal fibrosis
Pulmonary venous occlusion
Pulmonary artery vasoconstriction
Dyspnea
Exertional dyspnea
Disease(s) Associated with BMPR2
primary pulmonary hypertension
pulmonary venoocclusive disease

Mouse Phenotypes
abnormal lung vasculature morphology
increased lung endothelial cell proliferation
abnormal pulmonary alveolus morphology
Availability Mouse Genotype
Bmpr2tm1Kmi/Bmpr2+
Tg(Tagln-rtTA)E1Jwst/0
Tg(tetO-Bmpr2*R899X)#Jwst/0
Bmpr2tm1.1Enl/Bmpr2tm1.1Enl
Tg(Acvrl1-cre)L1Spo/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory