|
Symbol Name ID |
Esr2
estrogen receptor 2 (beta) MGI:109392 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Elevated circulating C-reactive protein concentration |
Elevated circulating hepatic transaminase concentration |
Elevated erythrocyte sedimentation rate |
Glucose intolerance |
Diabetes mellitus |
Type I diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Edema |
Joint swelling |
Pulmonary edema |
Fever |
Hematuria |
Pyuria |
Proteinuria |
Decreased cirrculating antimullerian hormone circulation |
Elevated circulating follicle stimulating hormone level |
Elevated circulating luteinizing hormone level |
Decreased serum estradiol |
Increased circulating free T3 |
Increased circulating free T4 concentration |
Decreased thyroid-stimulating hormone level |
| Disease(s) Associated with ESR2 | ||||||||||||||||||||||||||
| coronary artery disease | ||||||||||||||||||||||||||
| Graves' disease | ||||||||||||||||||||||||||
| ovarian dysgenesis 8 | ||||||||||||||||||||||||||
| pre-eclampsia | ||||||||||||||||||||||||||
| rheumatoid arthritis | ||||||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal response of heart to induced stress |
abnormal response to cardiac infarction |
decreased insulin secretion |
decreased circulating glucose level |
increased circulating glucose level |
increased circulating luteinizing hormone level |
increased circulating insulin-like growth factor I level |
decreased dopamine level |
ascites |
increased insulin sensitivity |
increased urine glycosaminoglycan level |
decreased serotonin level |
abnormal response/metabolism to endogenous compounds |
decreased physiological sensitivity to xenobiotic |
delayed wound healing |
|
| Availability | Mouse Genotype | ||||||||||||||||
| Esr2tm1Mma/Esr2tm1Mma | * | ||||||||||||||||
| Esr2tm1Unc/Esr2tm1Unc | |||||||||||||||||
| Esr2tm1.1Pcn/Esr2tm1.1Pcn Tg(KRT14-cre)1Ipc/0 (conditional) |
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| Esr2tm1.1Pcn/Esr2tm1.1Pcn Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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