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Symbol
Name
ID
Esr2
estrogen receptor 2 (beta)
MGI:109392
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abdominal pain
Anorexia
Depression
Apathy
Reduced social reciprocity
Polyphagia
Hyperactivity
Impulsivity
Agitation
Restless legs
Fatigue
Arthralgia
Chest pain
Epigastric pain
Disease(s) Associated with ESR2
coronary artery disease
Graves' disease
Parkinson's disease
pre-eclampsia
rheumatoid arthritis
systemic lupus erythematosus

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
impaired contextual conditioning behavior
impaired cued conditioning behavior
decreased exploration in new environment
abnormal spatial learning
increased aggression towards male mice
increased anxiety-related response
increased thigmotaxis
hyporesponsive to tactile stimuli
decreased vertical activity
decreased locomotor activity
decreased chemical nociceptive threshold
abnormal nociception after inflammation
abnormal sexual interaction
Availability Mouse Genotype
Esr2tm1Mma/Esr2tm1Mma
Esr2tm1Unc/Esr2tm1Unc *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory