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Symbol
Name
ID
Stx1a
syntaxin 1A (brain)
MGI:109355
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abdominal pain
Depression
Apathy
Personality changes
Disease(s) Associated with STX1A
Creutzfeldt-Jakob disease
Hirschsprung's disease

Mouse Phenotypes
behavior/neurological phenotype
impaired contextual conditioning behavior
abnormal cued conditioning behavior
abnormal latent inhibition of conditioning behavior
abnormal spatial working memory
abnormal depression-related behavior
decreased anxiety-related response
abnormal response to novel object
increased startle reflex
decreased grip strength
increased locomotor activity
abnormal social investigation
Availability Mouse Genotype
Stx1atm1b(EUCOMM)Hmgu/Stx1atm1b(EUCOMM)Hmgu
Stx1atm1Gwz/Stx1atm1Gwz *
Stx1atm1Tfuj/Stx1atm1Tfuj
Stx1atm1Migar/Stx1a+
Stx1atm1Tfuj/Stx1a+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory