|
Symbol Name ID |
Brca2
breast cancer 2, early onset MGI:109337 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Myelodysplasia |
Breast carcinoma |
Adenomatous colonic polyposis |
Colon cancer |
Neoplasm of the liver |
Pancreatic adenocarcinoma |
Iris melanoma |
Ciliary body melanoma |
Uveal melanoma |
Choroidal melanoma |
Prostate cancer |
Dysgerminoma |
Ovarian carcinoma |
Ovarian papillary adenocarcinoma |
Endometrial carcinoma |
Nephroblastoma |
Spinal cord tumor |
Medulloblastoma |
Cerebellar medulloblastoma |
Neuroblastoma |
Neoplasm of the lung |
Neoplasm |
Melanoma |
| Disease(s) Associated with BRCA2 | |||||||||||||||||||||||||
| breast cancer | |||||||||||||||||||||||||
| endometrial cancer | |||||||||||||||||||||||||
| Fanconi anemia | |||||||||||||||||||||||||
| Fanconi anemia complementation group D1 | |||||||||||||||||||||||||
| medulloblastoma | |||||||||||||||||||||||||
| nephroblastoma | |||||||||||||||||||||||||
| ovarian cancer | |||||||||||||||||||||||||
| pancreatic cancer | |||||||||||||||||||||||||
| prostate cancer | |||||||||||||||||||||||||
| uveal melanoma |
| Mouse Phenotypes | neoplasm |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
increased prostate intraepithelial neoplasia incidence |
increased T cell derived lymphoma incidence |
decreased incidence of tumors by chemical induction |
increased lymphoma incidence |
increased carcinoma incidence |
decreased tumor incidence |
increased tumor incidence |
decreased tumor latency |
|
| Availability | Mouse Genotype | |||||||||||
| Brca2tm1Cam/Brca2tm1Cam | ||||||||||||
| Brca2tm1Cbl/Brca2tm1Cbl | ||||||||||||
| Brca2tm1Hst/Brca2tm1Hst | ||||||||||||
| Brca2tm1Kamc/Brca2tm1Kamc | * | |||||||||||
| Brca2tm2.1Sks/Brca2tm2.1Sks | * | |||||||||||
| Brca2tm1Arge/Brca2+ | * | |||||||||||
| Brca2tm1Mbn/Brca2+ | ||||||||||||
| Brca2tm1Mhun/Brca2+ | ||||||||||||
| Brca2tm2.1Sks/Brca2tm1Brd | * | |||||||||||
| Brca2tm1Brn/Brca2tm1Brn Tg(Pbsn-cre)4Prb/0 (conditional) |
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| Brca2tm2Arge/Brca2tm2Arge Waptm1(cre)Arge/Waptm1(cre)Arge (conditional) |
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| Brca2tm1Arge/Brca2tm2Arge Waptm1(cre)Arge/Wap+ (conditional) |
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| Brca2tm1Mak/Brca2tm2Mak Tg(Lck-cre)548Jxm/0 (conditional) |
* | |||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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