Symbol Name ID |
Brca2
breast cancer 2, early onset MGI:109337 |
Darker colors indicate more annotations |
Human Phenotypes | Breast carcinoma |
Jaundice |
Abnormality of skin pigmentation |
Irregular hyperpigmentation |
Cafe-au-lait spot |
Multiple cafe-au-lait spots |
Hypopigmented skin patches |
Disease(s) Associated with BRCA2 | |||||||
breast cancer | |||||||
Fanconi anemia | |||||||
Fanconi anemia complementation group D1 | |||||||
ovarian cancer | |||||||
pancreatic cancer |
Mouse Phenotypes | abnormal branching of the mammary ductal tree |
decreased mammary duct terminal end bud number |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
abnormal skin morphology |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
absent epidermis stratum corneum |
abnormal epidermis stratum spinosum morphology |
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Availability | Mouse Genotype | |||||||||
Brca2tm1Cbl/Brca2tm1Cbl | ||||||||||
Brca2tm1Kamc/Brca2tm1Kamc | ||||||||||
Brca2tm1Mbn/Brca2+ | ||||||||||
Brca2tm2.1Sks/Brca2tm1Brd | ||||||||||
Brca2tm2Arge/Brca2tm2Arge Waptm1(cre)Arge/Waptm1(cre)Arge (conditional) |
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Brca2tm1Arge/Brca2tm2Arge Waptm1(cre)Arge/Wap+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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