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Symbol
Name
ID

Brca2
breast cancer 2, early onset
MGI:109337

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Abnormality of chromosome stability	Chromosomal breakage induced by crosslinking agents	Elevated circulating hepatic transaminase concentration	Diabetes mellitus	Cerebellar calcifications
Disease(s) Associated with BRCA2	Abnormality of chromosome stability	Chromosomal breakage induced by crosslinking agents	Elevated circulating hepatic transaminase concentration	Diabetes mellitus	Cerebellar calcifications
Fanconi anemia
Fanconi anemia complementation group D1
medulloblastoma
pancreatic cancer

Mouse Phenotypes		homeostasis/metabolism phenotype	abnormal DNA repair	abnormal double-strand DNA break repair	increased mortality induced by ionizing radiation	decreased incidence of tumors by chemical induction
Availability	Mouse Genotype	homeostasis/metabolism phenotype	abnormal DNA repair	abnormal double-strand DNA break repair	increased mortality induced by ionizing radiation	decreased incidence of tumors by chemical induction
	Brca2^tm1Cbl/Brca2^tm1Cbl
	Brca2^tm1Kamc/Brca2^tm1Kamc
	Brca2^tm2.1Sks/Brca2^tm2.1Sks	*
	Brca2^tm1Mhun/Brca2⁺
	Brca2^tm2.1Sks/Brca2^tm1Brd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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