About   Help   FAQ
Symbol
Name
ID
Kif1a
kinesin family member 1A
MGI:108391
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Decreased taste sensation
Ankle clonus
Spasticity
Lower limb spasticity
Spastic paraplegia
Progressive spastic paraplegia
Spastic gait
Scissor gait
Decreased number of peripheral myelinated nerve fibers
Decreased sensory nerve conduction velocity
Decreased nerve conduction velocity
Peripheral axonal neuropathy
Peripheral neuropathy
Sensorimotor neuropathy
Sensory impairment
Painless fractures due to injury
Distal sensory impairment
Cerebral atrophy
Cerebellar atrophy
Diffuse cerebellar atrophy
Cerebellar vermis atrophy
Ataxia
Dysmetria
Babinski sign
Absent speech
Hyperreflexia
Lower limb hyperreflexia
Areflexia
Hyporeflexia
Inability to walk
Unsteady gait
Intellectual disability
Global developmental delay
Seizures
Disease(s) Associated with KIF1A
autosomal dominant non-syndromic intellectual disability 9
hereditary sensory and autonomic neuropathy type 2A
hereditary sensory neuropathy type 2C
hereditary spastic paraplegia 30

Mouse Phenotypes
abnormal synaptic vesicle number
neuron degeneration
axon degeneration
abnormal nervous system physiology
abnormal synaptic vesicle clustering
Availability Mouse Genotype
Kif1atm1Noh/Kif1atm1Noh

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/13/2019
MGI 6.14
The Jackson Laboratory