Symbol
Name
ID

Alx4
aristaless-like homeobox 4
MGI:108359

Phenotype annotations related to limbs/digits/tail

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes

Genu valgum

Shortening of all distal phalanges of the fingers

Cone-shaped epiphyses of the phalanges of the hand

Shortening of all middle phalanges of the fingers

Broad thumb

Triphalangeal thumb

Arachnodactyly

Hallux valgus

Cone-shaped epiphyses of the toes

Brachydactyly

Metatarsus adductus

Metaphyseal widening

Dislocated radial head

Pes planus

Talipes equinovarus

Genu recurvatum

Carpal bone malsegmentation

Single transverse palmar crease

Joint contracture of the hand

Disease(s) Associated with ALX4

craniosynostosis

parietal foramina

Mouse Phenotypes		abnormal zone of polarizing activity morphology	abnormal limb morphology	polydactyly	preaxial polydactyly	short tibia
Availability	Mouse Genotype	abnormal zone of polarizing activity morphology	abnormal limb morphology	polydactyly	preaxial polydactyly	short tibia
	Alx4^Lst-2J/Alx4^Lst-2J
	Alx4^m1Btlr/Alx4^m1Btlr
	Alx4^M1Yzcm/Alx4^M1Yzcm
	Alx4^tm1Rwi/Alx4^tm1Rwi
	Alx4^Lst-2J/Alx4⁺
	Alx4^Lst-2J/Alx4^lst-J
	Alx4^lst-Alb/Alx4⁺		!		!
	Alx4^M1Yzcm/Alx4⁺
	Alx4^tm1Rwi/Alx4⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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