Symbol Name ID |
Smo
smoothened, frizzled class receptor MGI:108075 |
Darker colors indicate more annotations |
Human Phenotypes | Back pain |
Disease(s) Associated with SMO | |
pancreatic cancer |
Mouse Phenotypes | decreased chondrocyte proliferation |
abnormal cranium morphology |
abnormal basisphenoid bone morphology |
absent styloid process |
Meckel's cartilage hypoplasia |
short Meckel's cartilage |
abnormal sphenoid bone morphology |
small alisphenoid bone |
absent orbitosphenoid bone |
absent presphenoid bone |
absent pterygoid process |
abnormal temporal bone morphology |
small temporal bone squamous part |
abnormal ethmoid bone morphology |
abnormal tooth morphology |
abnormal incisor morphology |
absent lower incisors |
abnormal molar morphology |
abnormal molar cusp morphology |
fused molars |
abnormal ameloblast morphology |
absent Tomes' process |
abnormal enamel organ morphology |
abnormal stellate reticulum morphology |
abnormal inner dental epithelium morphology |
abnormal outer dental epithelium morphology |
absent enamel cord |
abnormal mandible morphology |
abnormal mandibular condyloid process morphology |
abnormal maxilla morphology |
absent lacrimal bone |
nasal bone hypoplasia |
absent palatine bone |
absent vomer bone |
small zygomatic bone |
absent incus |
absent gonial bone |
absent malleus |
absent stapes |
absent middle ear ossicles |
absent Reichert cartilage |
short humerus |
short ulna |
short fibula |
short tibia |
abnormal thyroid cartilage morphology |
decreased length of long bones |
short scapula |
abnormal skeleton development |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||
Smotm1Amc/Smotm2Amc H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Smotm1Amc/Smotm2Amc Tg(KRT14-cre)1Amc/0 (conditional) |
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Smotm1Amc/Smotm2Amc Tg(Col2a1-cre)10Amc/0 (conditional) |
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Smotm1Amc/Smotm2Amc Tg(Col2a1-cre)15Amc/0 (conditional) |
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Smotm1Amc/Smotm2Amc Tg(Col2a1-cre)3Amc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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