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Symbol
Name
ID
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
MGI:108074
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations

Mouse Phenotypes
increased cholesterol efflux
increased blood urea nitrogen level
abnormal circulating lipid level
increased circulating HDL cholesterol level
increased circulating cholesterol level
increased circulating phospholipid level
abnormal circulating protein level
increased circulating alanine transaminase level
increased circulating serum albumin level
dehydration
impaired skin barrier function
abnormal lipid level
abnormal sphingomyelin level
abnormal ceramide level
Availability Mouse Genotype
Sptlc2tm1Jia/Sptlc2+
Sptlc2tm1Yhir/Sptlc2tm1Yhir
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+  (conditional)
Sptlc2tm1Yhir/Sptlc2tm1Yhir
Tg(KRT5-cre)1Tak/0  (conditional)
Sptlc2tm2.1Jia/Sptlc2tm2.1Jia  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory